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Director of Material Operations - Biopharma

Executive Management
Jill Madden
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Job Reference: JO-2210-66327_1667851047


Fastnet Executive Search are delighted to partner once again with our long-standing client Biomarin in their search for a Director of Material Operations in their Cork site. BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. They target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. BioMarin will continue to focus on advancing therapies that are the first or best of their kind.

The Director of Material Operations is a key member of the Site Leadership team with accountability for the site Supply Chain function. Key aspects of this role include, material purchasing, warehouse operations, Drug Substance shipping, bill of material and recipe management, rough cut and detailed capacity planning, plant master scheduling and finite scheduling for packaging and drug product. This crucial role is also a member of the wider BioMarin Supply Chain community and participates in network initiatives and efforts, including improving governance, and delivering Supply Chain Strategic objectives.

The team ensures manufacturing and packaging plans are feasible within the installed plant capacity and that potential capacity constraints can be resolved across the network. They also co-ordinate cross-functional activity at the site with the ultimate objective of meeting supply targets allocated through the S&OP process. Coupled with this, the function supports manufacturing and packaging operations directly through the timely supply of materials and the maintenance of accurate inventory within onsite and off-site storage locations.


· Partner with Global Procurement category managers to align material requirements with sourcing strategies that optimize spend and availability.

· Align with Global Supply Planning to ensure the capacity made available to the production plan accurately reflects actual plant capabilities across all work centres, including facilities-engineering, quality control, quality assurance, lot disposition in addition to manufacturing and packaging.

· Liaise with Global logistics in support of timely deliveries, and site transfers of raw materials, intermediates, and inventory.

· Participate in Network strategy teams working to align future plant capabilities with emerging business needs.

-BioMarin Information Technology to continually define and update the technology roadmap in a manner that develops plant capability in alignment with network and site strategy.

-Tech transfer and product development (CMC) teams to ensure that the materials, capacity and staff needed to deliver the pipeline in accordance with defined milestones are provided when required.

-Manufacturing and packaging work centres to provide, shop floor control and detailed capacity analysis as required.

· Maintain and develop a culture focused on safety and quality in the Material Operations team

· Drive a functional excellence agenda through the Material Operations Functional Lead team in support of overall site operational excellence roadmap

· Ensure correct resources and storage capacity is in place to support site growth over the long range plan

· Accountability for Master Scheduling: Define and update, in a regular and routine fashion, with work center owners and identified process experts, the parameters needed for detailed capacity planning-including lead times, yields, success rates, run rates and shop calendars.

· Manage escalation and decision-making around planning time fence crashes.

· Participate as an active member of the Site Leadership Team providing leadership and support to the Material Operations team and the site.

· Ensure that material delivery and release dates align with the production plan with support from Global Procurement, as required.

· Key site interface with purchased material suppliers, building relationships, measuring and improving supplier performance and material cost.

· Ensure trade and local revenue compliance in relation to material shipping to and from the site with support from Global Logistics.

· Participate in (internal or external plant governance), leading or facilitating as needed, to deliver the Site Strategic Business Plan.

· Work with master data owners to ensure that data used for production planning and scheduling are up to date.

· Lead transformation change initiatives as requested and required by Site Leadership in support of the Site Strategic Business Plan.

· Create and maintain a diverse and inclusive workplace that is aligned with the BioMarin culture.

· Build focus and engagement by fostering opportunities for ownership, impact and continual professional development.


· Degree in Business, Science / Engineering, Operations Management, or Industrial Engineering required

· APICS certification and/or supply chain education desirable

· Other continuing education initiatives highly desirable (e.g. Six Sigma, Lean Manufacturing, etc.)

· At least 12 years GMP/GCP compliant Biopharma operations experience required.

· Experience with Master Scheduling, Inventory Analysis and Management, ERP (Oracle or SAP) systems, and new product launches required

· Demonstrated ability to partner with other functional groups to achieve business objectives required

· Experience successfully leading transformational change

Fastnet has a strict confidentiality policy - please be assured that your details will never be forwarded to any third party without your consent.

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Jill Madden
Jill Madden
Senior Client Partner, Fastnet Executive Search
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